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Acetato de octreotida, 83150-76-9

Acetato de octreotida, 83150-76-9

  • CAS #:83150-76-9
  • Nome do produto:Acetato de octreotida
  • Tamanho:1g ou mais
  • Habilidade da fonte:500g / duas semanas
  • FOB Preço:Email
  • Condições de pagamento:T / T
  • Prazo de execução:Dentro de 12 horas após o recebimento do pagamento
  • Embalagem:Maneiras discretas de embalagem para passe alfandegário garantidas
  • Entrega:por expresso (FedEx, UPS, DHL, EMS), por via aérea
  • Download:MSDS
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  • MSDS
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Octreotide Acetate-Physiochemical properties

Sequence(Single-Letter Code): (d)FCF(d)WKTCT-ol,(Disulfide bond)

Sequence(Three-Letter Code): H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol,(Disulfide bond)

Molecular Formula: C49H66N10O10S2

Peso molecular: 1019.24 g / mol

Armazenamento: armazenar em local fresco, seco e ventilado

PSA: 382.82000

LogP: 3.02100

Octreotide Acetate Description

Alternate Names:Octreotide AcetateDARAMONOL;L-cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(2-hydroxy-1-(hydroxymethyl) propyl)-cyclic (2->7)-disulfide, (R-(R*,R*));ctreotide;Ocetreotide, Acetate;L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl-, cyclic (2?7)-disulfide;OXTREOTIDE;[R-(R*,R*)]-D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxy-methyl)propyl]-cysteinamide cyclic(2->7)-disulfide;Octreotide acetate,SMS 201995; Sandostatin

Octreotide Acetate is a longer acting synthetic octapeptide analog of naturally occurring somatostatin. Octreotide Acetate inhibits the secretion of gastro-entero-pancreatic peptide hormones and the release of growth hormone. Octreotide reduces gastrointestinal motility and inhibits contraction of the gall bladder.

Octreotide acetate (Sandostatin) is an octapeptide congener of native somatostatin, inhibits the secretion of insulin and glucagon. It reduces production of IGF-1 and IGF-2 by the liver by modulation of growth-hormone secretion from the pituitary gland. [1]
The insulin-like growth factors IGF-1 and IGF-2, endogenously produced polypeptide hormones and potent stimulators of cell proliferation, are under investigation as clinical targets in prostate cancer.
Octreotide acetate decreased the urinary excretion of uric acid as well as the plasma concentrations of glucagon and insulin. Octreotide acetate decreased the urinary excretion of sodium and chloride without significiant influence on creatinine clearance, while the concentrations of lactic acid, pyruvic acid in blood, and cyclic AMP in plasma were not changed. [1]

Octreotide Acetate Application

Acromegalia
Carcinoid syndrome
VIPomas

Octreotide Acetate References

[1] Tetsuya yamamoto, Yuji moriwaki et al. Effect of Octreotide acetate on the Plasma Concentration and Urinary Excretion of Uridine and Purine Bases. Endocrine Journal 2002, 49(2),139-144.

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