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Somatostatin Acetate,38916-34-6

Somatostatin Acetate,38916-34-6

     

  • CAS#:38916-34-6
  • Product Name:Somatostatin Acetate
  • Size:1g or more
  • Supply Ability:500g/two weeks
  • FOB Price:Email
  • Payment Terms:T/T
  • Lead time:Within 12 hours after receiving payment
  • Packing:Discreet ways of packing for Customs pass guaranteed
  • Delivery:by express (FedEx,UPS,DHL,EMS), by air
  • Download:MSDS
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Somatostatin Acetate-Physiochemical properties

      Sequence(Single-Letter Code): AGCKNFFWKT FTSC (Disulfide bond)

      Sequence(Three-Letter Code): H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (Disulfide bond)

      Number of residues:     14aa

      Molecular weight:     1637.88 g/mol

      Extinction coefficient: 5690 M-1cm-1

      Iso-electric point:     pH 9.11

      Net charge at pH 7:     1.9

      Estimated solubility:     Poor water solubility.

      Storage:store in cool, dry, ventilated place

      PSA:     663.83000

      LogP:     2.28620

      EINECS:     254-186-5

      MDL:     MFCD00076762

Somatostatin Acetate Description

      Alternate Names:Somatostatin Acetate,GROWTH HORMONE RELEASE INHIBITING FACTOR (HUMAN, OVINE, PORCINE, RAT, MOUSE);GROWTH HORMONE RELEASE INHIBITING FACTOR (HUMAN, OVINE, PORCINE, RAT, MOUSE) 2ACOH 6H2O;H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH;H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (COUPLED TO BSA);H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (COUPLED TO KLH);H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH, CYS3,14, CYCLIC;H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (DISULFIDE BRIDGE: 3-14);GIF (HUMAN, OVINE, PORCINE, RAT, MOUSE)

This is a hormone that helps the body to manage the endocrine system by impacting cell proliferation and neurotransmission by interacting with somatostatin receptors (G protein-coupled) to inhibit the release of secondary hormones throughout the body.

There are two active forms that are often produced by preproprotein, one containing 28 amino acids and one that contains 14 amono acids. Vertebrates have six different genes that participate in somostatin production, allowing it to perform a variety of functions depending on the animal in which it is displayed.

Somatostatin may be produced in an animal’s digestive system to encourage acid producing parietal cells while decreasing production of histamine, gastrin and secretin. It is also present in the gastrointestinal system to stop the release of overactive gastrointestinal hormones to suppress pancreatic hormones or decrease the rate in which the gastric system empties while improving blood flow to the intestines.

This is classified as an inhibitory hormone which can be spread to many other areas of the body in an animal, particularly in inhibiting the release of thyroid stimulating hormone.

Somatostatin Acetate References

1. Somatostatin-14 influences pituitary-ovarian axis in peripubertal rats.
Histochemistry and Cell Biology2008-10-01
2. Evaluation of different methods for assessment of insulin sensitivity in Gottingen minipigs: introduction of a new, simpler method.
Audio, Transactions of the IRE Professional Group on2009-10-01
3. Effects of somatostatin on the responses of rostrally projecting spinal dorsal horn neurons to noxious stimuli in cats.
Korean Journal of Physiology and Pharmacology2008-10-01
4. Inhibition of pancreatic somatostatin release in response to glucose.
Biochemical and Biophysical Research Communications1978-06-29
5. Somatostatin and behaviour: the need for genetically engineered models.
Journal of Physiology-Paris2000-05-01

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